We have not yet certified QT to work with Vista and I know that there are at least some issues. One of them has to do with new security stuff in Vista. It interferes with QuoteTracker saving files, which mean updates are not saved, user settings, etc. If you turn off UAC(see note below), it should resolve the problem. Alternately, you can try copying the QT folder and its subfolders somewhere like (C:\QuoteTracker for example, instead of C:\Program Files\QuoteTracker). So long as its outside of the "Program Files" folder.
Just make the folder right off the root and copy all files there. Everything should work ok then, at least according to some Vista information I received.
The other known issue is the buttons that QT adds to the caption, like the LINK buttons, do not show in vista.
UAC=User Account Control
Here's how to disable it:
http://www.mydigitallife.info/2006/12/19/turn-off-or-disable-user-account-control-uac-in-windows-vista/